Vic Gentils was born in England as the son of a French father and a Flemish mother. He studied at the National Higher Institute for Fine Arts in Antwerp in the 1940s.
In the beginning of the 1950s, he mainly painted. Later he concentrated mainly on experimental sculpting and assembly art with wooden and metal recuperation materials such as piano parts. His assemblages are very recognizable and belonged to the avant-garde atmosphere that connected many post-war artists at the time.
In 1958, Gentils founded the artists' group G58 in the Hessenhuis in Antwerp. In 1964 he represented Belgium at the Venice Biennale and also participated in the Biennial of Kassel. In 1967 followed participation in the São Paulo Biennale. His work is widespread and can be seen at the M HKA and the Royal Museums of Fine Arts of Belgium.